Abstract: The article aims to explore the changes in the spatial pattern of regional economic development in Beijing-Tianjin-Hebei region and analyze the reasons. We analyzes the evolution of the spatial pattern of economic development scale and structure from 174 county units in Beijing-Tianjin-Hebei region from 2006 to 2016 by the exploratory spatial method. It is found that the differences in regional economic scale and structure of Beijing-Tianjin-Hebei region have a significant trend of changing in stages. The polarization of county economic development is obvious and the ratio of per capita GDP and tertiary industry GDP have significant, positive spatial autocorrelation, showing the spatial agglomeration distribution and the typical "core-edge" pattern. The pattern of spatial development axis of regional economy has been formed gradually and each functional area develops an economic development characteristic that conforms to the functional positioning of its own.The paper suggests that the main factors affecting the regional economic pattern in Beijing-Tianjin-Hebei region are economic development foundation, regional economic policy and geographical location.Finally, we put forward the policy recommendations for the structural optimization and coordinated development according to strategic function of Beijing-Tianjin-Hebei region.